18,057 research outputs found

    LANDING LOADS AND DYNAMICS OF THE X-15 AIRPLANE

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    Measurements of loads, accelerations, and displacements of x-15 aircraft and landing gear during landing impac

    Inhibition of monocyte complement receptor enhancement by low molecular weight material from human lung cancers

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    We have studied the effect of dialysates from lung cancer homogenates to alter both the expression of complement (C3b) receptors per se and also to inhibit leucoattractant-induced enhancement of complement rosettes on monocytes from healthy individuals. Enhancement and enhancement-inhibition by tumour extracts were compared with material derived from normal lung excised from distance from the tumour. There was no significant difference between tumour homogenate (TH) and normal lung homogenate (NLH) in terms of enhancement of complement rosettes per se. In contrast, TH produced a dose- and time-dependent inhibition of leucoattractant-induced enhancement of C3b rosettes which was significantly different from that obtained with NLH. This enhancement-inhibition was observed with four undifferentiated, four squamous and three adenocarcinomas of lung. The degree of enhancement-inhibition was not related to the type of tumour or varying accompanying histological features such as necrosis and the degree of infiltration with inflammatory cells. Following gel filtration on Sephadex G-50 each type of cancer gave a major peak of inhibitory activity which eluted with molecules having an apparent molecular size of approximately 3,000 daltons. A second larger peak (8,000-10,000 daltons) was also detected with extracts from the undifferentiated and adenocarcinomas. These results support previous findings, mainly from experimental animals, indicating that 'anti-macrophage/monocyte principles' are elaborated from certain tumour types

    Application of moderate resolution band models to the prediction of heat transfer from rocket exhaust plumes

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    Computer program for resolution band model prediction of heat transfer from rocket exhaust plume

    Acanthocephalan Development: Morphogenesis of Larval Moniliformis Dubius

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    Paper by J. E. Byram and Kay W. Byra

    Entanglement generation in harmonic chains: tagging by squeezing

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    We address the problem of spring-like coupling between bosons in an open chain configuration where the counter-rotating terms are explicitly included. We show that fruitful insight can be gained by decomposing the time-evolution operator of this problem into a pattern of linear-optics elements. This allows us to provide a clear picture of the effects of the counter-rotating terms in the important problem of long-haul entanglement distribution. The analytic control over the variance matrix of the state of the bosonic register allows us to track the dynamics of the entanglement. This helps in designing a global addressing scheme, complemented by a proper initialization of the register, which quantitatively improves the entanglement between the extremal oscillators in the chain, thus providing a strategy for feasible long distance entanglement distribution.Comment: 8 pages, 8 figures, RevTeX

    Super-Rough Glassy Phase of the Random Field XY Model in Two Dimensions

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    We study both analytically, using the renormalization group (RG) to two loop order, and numerically, using an exact polynomial algorithm, the disorder-induced glass phase of the two-dimensional XY model with quenched random symmetry-breaking fields and without vortices. In the super-rough glassy phase, i.e. below the critical temperature TcT_c, the disorder and thermally averaged correlation function B(r)B(r) of the phase field θ(x)\theta(x), B(r)=ˉB(r) = \bar{} behaves, for rar \gg a, as B(r)A(τ)ln2(r/a)B(r) \simeq A(\tau) \ln^2 (r/a) where r=rr = |r| and aa is a microscopic length scale. We derive the RG equations up to cubic order in τ=(TcT)/Tc\tau = (T_c-T)/T_c and predict the universal amplitude A(τ)=2τ22τ3+O(τ4){A}(\tau) = 2\tau^2-2\tau^3 + {\cal O}(\tau^4). The universality of A(τ)A(\tau) results from nontrivial cancellations between nonuniversal constants of RG equations. Using an exact polynomial algorithm on an equivalent dimer version of the model we compute A(τ){A}(\tau) numerically and obtain a remarkable agreement with our analytical prediction, up to τ0.5\tau \approx 0.5.Comment: 5 pages, 3 figure

    Physical controls on orographic cirrus inhomogeneity

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    Optical depth distributions (P(σ)) are a useful measure of radiatively important cirrus (Ci) inhomogeneity. Yet, the relationship between P(σ) and underlying cloud physical processes remains unclear. In this study, we investigate the influence of homogeneous and heterogeneous freezing processes, ice particle growth and fallout, and mesoscale vertical velocity fluctuations on P(σ) shape during an orographic Ci event. We evaluate Lagrangian Ci evolution along kinematic trajectories from a mesoscale weather model (MM5) using an adiabatic parcel model with binned ice microphysics. Although the presence of ice nuclei increased model cloud cover, our results highlight the importance of homogeneous freezing and mesoscale vertical velocity variability in controlling Ci P(σ) shape along realistic upper tropospheric trajectories

    'She's like a daughter to me': insights into care, work and kinship from rural Russia

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    This article draws on ethnographic research into a state-funded homecare service in rural Russia. The article discusses intersections between care, work and kinship in the relationships between homecare workers and their elderly wards and explores the ways in which references to kinship, as a means of authenticating paid care and explaining its emotional content, reinforce public and private oppositions while doing little to relieve the tensions and conflicts of care work. The discussion brings together detailed empirical insights into local ideologies and practices as a way of generating new theoretical perspectives, which will be of relevance beyond the particular context of study

    The N-Terminus of Apolipoprotein A-V Adopts a Helix-Bundle Molecular Architecture

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    Previous studies of recombinant full-length human apolipoprotein A-V (apoA-V) provided evidence of the presence of two independently folded structural domains. Computer-assisted sequence analysis and limited proteolysis studies identified an N-terminal fragment as a candidate for one of the domains. C-Terminal truncation variants in this size range, apoA-V(1-146) and apoA-V(1-169), were expressed in Escherichia coli and isolated. Unlike full-length apoA-V or apoA-V(1-169), apoA-V(1-146) was soluble in neutral-pH buffer in the absence of lipid. Sedimentation equilibrium analysis yielded a weight-average molecular weight of 18811, indicating apoA-V(1-146) exists as a monomer in solution. Guanidine HCl denaturation experiments at pH 3.0 yielded a one-step native to unfolded transition that corresponds directly with the more stable component of the two-stage denaturation profile exhibited by full-length apoA-V. On the other hand, denaturation experiments conducted at pH 7.0 revealed a less stable structure. In a manner similar to that of known helix bundle apolipoproteins, apoA-V(1-146) induced a relatively small enhancement in 8-anilino-1-naphthalenesulfonic acid fluorescence intensity. Quenching studies with single-Trp apoA-V(1-146) variants revealed that a unique site predicted to reside on the nonpolar face of an amphipathic R-helix was protected from quenching by KI. Taken together, the data suggest the 146 N-terminal residues of human apoA-V adopt a helix bundle molecular architecture in the absence of lipid and, thus, likely exist as an independently folded structural domain within the context of the intact protein

    Optimal purification of thermal graph states

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    In this paper, a purification protocol is presented and its performance is proven to be optimal when applied to a particular subset of graph states that are subject to local Z-noise. Such mixed states can be produced by bringing a system into thermal equilibrium, when it is described by a Hamiltonian which has a particular graph state as its unique ground state. From this protocol, we derive the exact value of the critical temperature above which purification is impossible, as well as the related optimal purification rates. A possible simulation of graph Hamiltonians is proposed, which requires only bipartite interactions and local magnetic fields, enabling the tuning of the system temperature.Comment: 5 pages, 4 figures v2: published versio
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